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The effect and mechanism of labor analgesia on the outcome of scar uterus second pregnancy

The effect and mechanism of labor analgesia on the outcome of scar uterus second pregnancy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023899
Enrollment
Unknown
Registered
2019-06-17
Start date
2019-10-15
Completion date
Unknown
Last updated
2019-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain management

Interventions

experimental group :epidural labor analgesia
control group:non-analgesia

Sponsors

Hubei Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 48 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: postnatal examination and routine laboratory examination were complete after admission, and the selected subjects met the relevant diagnostic criteria in diagnosis and treatment of scar uterine pregnancy and prognosis. 1) a history of cesarean section of the lower segment of uterus; 2) good wound healing without infection; 3) normal bone birth canal, headless basin is not weighed; 4) the previous cesarean section indication does not exist, and no new cesarean section indication is found; 5) the pregnancy is more than 19 months from the previous cesarean section; 6) no scar loss in the lower uterine segment observed by prenatal ultrasound; 7) the patient is willing to conduct vaginal trial birth after understanding the advantages and disadvantages of vaginal delivery and another cesarean section; 8) with good monitoring equipment, it can carry out operation, blood transfusion and rescue at any time; 9) no contraindications for epidural puncture anesthesia. Only if all the above conditions are met can they be included.

Exclusion criteria

Exclusion criteria: 1) the previous cesarean section was performed in classical style, and the previous uterine incision was inverted "T" or "J" shaped incision; 2) ) history of repeated cesarean section injury, such as uterine perforation, myomectomy, uterine rupture, extensive and deep uterine operation history; 3) > history of 2 cesarean sections; 4) Serious pregnancy complications and complications, and no other complications of internal and surgical procedures that are not suitable for vaginal delivery (such as placenta previa); 5) incomplete clinical records and maternal inability to cooperate with the study; 6) contraindication of epidural anesthesia; 7) mothers or their families are not willing to accept this study. Any of the above conditions should be excluded.

Design outcomes

Primary

MeasureTime frame
Labor time;Oxytocin use;The perineum situation;Postpartum and postpartum blood loss;Vaginal delivery success rate;Adverse reactions occur;Sex of newborn;Neonatal birth weight;Apgar score at 1min and 5min after birth;VAS analgesic score;Ramsay score;ACTH;IL-10;Cor;Blood sugar levels;IL-6;TNF-a;beta-endorphin;

Countries

China

Contacts

Public ContactShen Chan

Hubei Maternal and Child Health Care Hospital

sunnyabs1215@163.com+86 18986161976

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026