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Establishment of ocular surface comprehensive evaluation system and ocular surface assessment of safety and adverse effects of contact lens wearers

Establishment of ocular surface comprehensive evaluation system and ocular surface assessment of safety and adverse effects of contact lens wearers

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023876
Enrollment
Unknown
Registered
2019-06-15
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contact lens related complications

Interventions

Group 2:wearing rigid gas permeable contact lens
Control group1:Artificial tear(HYCOSAN, Germany)

Sponsors

The Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Follow-up subjects inclusion criteria: (1) aged 20-30 years old; (2) non contact lens wear history or wearing soft contact lens 6 months), weekly wear (> 5 days), daily (> 8 hours), contact lenses brand, type, degree, and self-contained frame glasses; (3) tear collection can reach 45µl; (4) can accept the entire set of experimental procedures and operations; (5) signing informed consent.

Exclusion criteria

Exclusion criteria: Follow-up subjects/ cross-sectional subjects excluded criteria: (1) has systemic or ocular allergic diseases; (2) have systemic diseases that can affect the health of the ocular surface, such as hypertension, diabetes, Sjogren's syndrome, thyroid disease, mental illness, etc.; (3) have eye diseases such as ocular surface inflammation, keratoconus, ocular tumor, glaucoma, etc.; (4) have a history of eye surgery; (5) have a history of smoking and / or alcohol abuse; (6) have systemic and / or eye medication; (7) pregnancy or lactation or menopausal women.

Design outcomes

Primary

MeasureTime frame
Vessel diameter;Vessel length;Axial blood velocity;Cross-sectional blood flow velocity;Cross-sectional flow;IL-1ß concentration;IL-6 concentration;IL-8 concentration;Conjunctival coverage;The temporal offset lag;OSDI score;QIRC score;Flat curvature;Steep curvature;Average curvature;Corneal pupil central thickness;Thickness of apex of anterior corneal surface;Thinnest corneal thickness;Efron score;TBUT;Schirmer I;Cell density;????;Dendritic length;

Countries

China

Contacts

Public ContactLIANG HU
hul@mail.eye.ac.cn+86 13867710883

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026