Contact lens related complications
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Follow-up subjects inclusion criteria: (1) aged 20-30 years old; (2) non contact lens wear history or wearing soft contact lens 6 months), weekly wear (> 5 days), daily (> 8 hours), contact lenses brand, type, degree, and self-contained frame glasses; (3) tear collection can reach 45µl; (4) can accept the entire set of experimental procedures and operations; (5) signing informed consent.
Exclusion criteria
Exclusion criteria: Follow-up subjects/ cross-sectional subjects excluded criteria: (1) has systemic or ocular allergic diseases; (2) have systemic diseases that can affect the health of the ocular surface, such as hypertension, diabetes, Sjogren's syndrome, thyroid disease, mental illness, etc.; (3) have eye diseases such as ocular surface inflammation, keratoconus, ocular tumor, glaucoma, etc.; (4) have a history of eye surgery; (5) have a history of smoking and / or alcohol abuse; (6) have systemic and / or eye medication; (7) pregnancy or lactation or menopausal women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vessel diameter;Vessel length;Axial blood velocity;Cross-sectional blood flow velocity;Cross-sectional flow;IL-1ß concentration;IL-6 concentration;IL-8 concentration;Conjunctival coverage;The temporal offset lag;OSDI score;QIRC score;Flat curvature;Steep curvature;Average curvature;Corneal pupil central thickness;Thickness of apex of anterior corneal surface;Thinnest corneal thickness;Efron score;TBUT;Schirmer I;Cell density;????;Dendritic length; | — |
Countries
China