A multicenter study for HEAD-US-C scale in evaluation of joints in patients with hemophilia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023872

Enrollment

Unknown

Registered

2019-06-15

Start date

2019-07-01

Completion date

Unknown

Last updated

2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia A

Interventions

Gold Standard:ultrasound assessment of hemophiliac joints

Index test:HEAD-US-C scale

Eligibility

Sex/Gender

Male

Age

4 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. 4 years of age or older; 2. Must have a diagnosis of moderate or severe hemophilia A.

Exclusion criteria

Exclusion criteria: 1. A history of joint surgery; 2. A history of FVIII inhibitor-positive; 3. Other diseases with ultrasound findings of arthropathy;

Design outcomes

Primary

Measure	Time frame
Effusion;Hypertrophic synovium;Doppler signals in haemophilic synovium;SPE, SEN, ACC, AUC of ROC;	—

Secondary

Measure	Time frame
Bone;Cartilage;	—

Countries

China

Contacts

Public ContactLi Jun

Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC

lijun@ihcams.ac.cn+86 022-23909133

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026