Knee ACL reconstruction
Conditions
Interventions
0.375% ropivacaine:0.375% ropivacaine
ropivacaine plus ketamine:0.375% ropivacaine plus ketamine
ropivacaine plus i.v. ketamine:0.375%ropivacaine plus i.v. ketamine
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 25 to 45 years; 2. ASA I~II level; 3. BMI 20~26kg/m2; 4. Patients undergoing elective knee ACL reconstruction.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating woman; 2. History of allergy to local anesthetics; 3. Mental and neurological diseases; 4. Diabetes and peripheral neuropathy or injury; 5. Patients with systemic diseases such as severe liver and kidney, heart and lung; 6. History of chronic pain; 7. Recent use of painkillers, hormones, and drug abuse history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative NRS pain score;AUC of NRS values; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative rescue analgesia time;satisfactory score;sleep at 1st night;rebound pain score;rescue analgesics; | — |
Countries
China
Contacts
Public ContactJiehao Sun
Department of anesthesiology, the First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed