Effects of different anesthetic drugs on cerebral hemodynamics in patients with subarachnoid hemorrhag

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023830

Enrollment

Unknown

Registered

2019-06-13

Start date

2017-07-01

Completion date

Unknown

Last updated

2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aneurysmal subarachnoid hemorrhage

Interventions

Group P:Propofol

Group S:Sevoflurane

Group E:Etomidate

Group DP:Dexmedetomidate+Propofol

Group DS:Dexmedetomidate+Sevoflurane

Group DS:Dexmedetomidate+Etomidate

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with aSAH, as well as underwent total cerebral angiography and interventional embolization therapy using digital subtraction angiography (DSA). For undergoing surgery, patients aged 18 years or older, with the American Society of Anesthesiology levels I to III, the Glasgow Coma Scale score of 13 or more and World Federation of Neurological Societies levels of I to III.

Exclusion criteria

Exclusion criteria: With serious cardiovascular disorders, disorders of the bronchus or lung, drugs allergy, non-aneurysmal subarachnoid hemorrhage and disagreement with consent.

Design outcomes

Primary

Measure	Time frame
time to peak;relative brain circulation time;average velocity of blood flow in the middle cerebral artery;	—

Secondary

Measure	Time frame
MoCA score;GOS score;	—

Countries

China

Contacts

Public ContactYing Nie

Guangdong 999 Brain Hospital

drnieying@163.com+86 13609015565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026