acute coronary syndrome
Conditions
Interventions
Brilinta group:Patiens will be given Brilinta
Taiyi group:Patients will be given TaiYi.
Sponsors
Tianjin Union Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years, regardless of gender; 2. Weight 50 kg or more; 3. Meet the diagnose standard of acute coronary syndrome (ACS); 4. Patients planning to undergo PCI; 5. To be able and willing to sign informed consent and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1. Bleeding symptoms (e.g. Hematemesis,Black stool, severe or recurrent nosebleed, hemoptysis, apparent hematuria, gastrointestinal bleeding or intracranial bleeding, or suspected vascular malformation (such as aneurysm),If he/she has a history of abnormal bleeding (e.g. abnormal bleeding at tooth extraction), or if he/she or his/her immediate family member has coagulation or bleeding disease (e.g. hemophilia); 2. Acute patients with st-segment elevation myocardial infarction after thrombolytic therapy; 3. Suspected patients with aortic dissection; 4. The stenosis degree of the left main artery is suspected to be more than 50%; 5. The total number of stent implantation is expected to be > 3 ; 6. Patients with negative coronary artery CT (whether or not to receive coronary artery CT was determined by the researcher); 7. Serious illness; Patients, life expectancy 1.3 times the upper limit of normal value or international standard ratio (INR) >2.0; 20. Platelet count (PLT) 600×10^9/L; 21. Hemoglobin level <10g/dL; 22. Cannot tolerate 28-day couplets; Patients treated with antiplatelet agents; 23. Positive pregnancy test results of women of reproductive age during screening; 24. Women in the study who were willing to conceive, A lactating woman; 25. The researcher believes that the patient has other conditions that are not suitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet aggregation rate; | — |
Countries
China
Contacts
Public ContactZhuhua Yao
Tianjin Union Medical Center
Outcome results
None listed