acute myocardial infarction
Conditions
Interventions
FOND:Use fondaparinux after primary percutaneous coronary intervention
LMWH:Use low molecular weight heparin after primary percutaneous coronary intervention
Sponsors
Shanxi Cardiovascular Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged =18 years, < 85 years; 2. Meets the diagnostic criteria of acute myocardial infarction; 3. PPCI was performed; 4. The patient or legal representative has been informed of the nature of the study, understands the protocol, is able to ensure compliance, and signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic or contraindicated to anticoagulant and antiplatelet drugs; 2. Cardiac shock, malignant ventricular arrhythmia and mechanical complications were found; 3. CABG was performed; 4. Patients with clear indications of anticoagulation after PPCI; 5. Patients who have long-term anticoagulation indication; 6. Any bleeding tendency, severe blood disease, intracranial parenchymal aneurysms, arteriovenous malformations, suspected aortic dissection, ischemic stroke within the last 6 months, transient ischemic attack or intracranial bleeding history, gastrointestinal and urinary bleeding history within the last 2 weeks; 7. Severe anemia and immune diseases, or (and) hormone therapy; 8. Concurrent diseases such as active infection or cancer ,life expectancy < 12 months; 9. Coagulation dysfunction or moderate or severe insufficiency of liver and kidney function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 30d NACE (MACCE and BARC3-5 bleeding); | — |
Countries
China
Contacts
Public ContactJian An
Shanxi Cardiovascular Hospital
Outcome results
None listed