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Clinical efficacy of arsenic trioxide combined with carboplatin for neoadjuvant chemotherapy for locally advanced cervical cancer

Clinical efficacy of arsenic trioxide combined with carboplatin for neoadjuvant chemotherapy for locally advanced cervical cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023822
Enrollment
Unknown
Registered
2019-06-13
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

Sponsors

The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Aged 20-60 years; 2 Patients with stage IB2, IIA2, IIB cervical cancer; 3 Normal blood analysis, liver and kidney function before treatment; 4 No evidence of distant metastasis; 5 No serious heart, liver, kidney and blood system and other important organ diseases; 6 Patients have signed the informed consent

Exclusion criteria

Exclusion criteria: 1 Early or small lesions do not require neoadjuvant chemotherapy patients; 2 cachexia:PS score = 3 points, KPS score < 70 points; 3 Active infection or bleeding; 4 Complete intestinal obstruction; 5 Uncontrolled psychosis; 6 Pregnant and lactating women; 7 Allergic constitution, or known to arsenic allergy patients; 8 Late no possibility of surgery patients; 9 Patients who are unwilling to receive neoadjuvant chemotherapy combined with surgery in the advanced stage; 10 Patients with severe comorbidities; 11 Patients who cannot tolerate chemotherapy and surgical words; 13 Patients who have participated in other clinical trials in the last 3 months; 12 Any other conditions that the investigator considers unsuitable for participation in this trial.

Design outcomes

Primary

MeasureTime frame
efficiency evaluation;

Countries

China

Contacts

Public ContactLi Daocheng

The First Affiliated Hospital of Guangzhou University of Chinese Medicine

460824332@qq.com+86 13710356413

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026