Cognitive/affective disorders and postoperative pain caused by radical mastectomy and chemotherapy
Conditions
Interventions
test group:Oral magnesium threonate
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Female
Age
17 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 70 years,woman, VAS score <7 points; 2) Breast cancer is planned for breast cancer surgery and patients undergoing postoperative chemotherapy; 3) With the approval of the hospital ethics committee, the patient volunteers and signs the informed consent form; 4) Subjects can objectively describe the symptoms and follow the product dose and visit plan; 5) The expected survival period is more than 6 months.
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women; 2) History of chronic pain, drug addiction and history of mental illness; 3) Suffering from severe respiratory system, cardiovascular disease, liver and kidney dysfunction, immune system diseases and other tumors; 4) Analgesics, antiepileptics, antidepressants, and drugs that affect Mg metabolism (thiazine diuretics, loop diuretics, magnesium antacids, calcium channel blockers, penicillamine, cortex) Hormone, etc.) 5) Those suffering from allergic diseases, allergic to the body; those who are allergic to magnesium threonate products; 6) Patients who participated in any randomized controlled product trials within 3 months prior to the trial (including the trial product); 7) Sponsors or researchers or their family members who are directly involved in the trial; 8) The investigator believes that there is a reason for not being selected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sitting experiment;Plasma Mg2+ concentration;Quality of life assessment;Pain assessment;Mental and psychological factors assessment; | — |
Countries
China
Contacts
Public ContactDong Huang
The Third Xiangya Hospital of Central South University
Outcome results
None listed