chronic valvular disease complicated with atrial fibrillation
Conditions
Interventions
experimental group :Valvular surgery combined with maze IV surgery
control group:Valvular surgery
Sponsors
the Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients who are scheduled to undergo surgery at the above centers from August 1, 2018 to August 31, 2020: 1) Aged 35 to 70 years, male or female; 2) The history of valvular disease is more than 3 years; 3) The history of atrial fibrillation can meet any of the following: a. Persistent atrial fibrillation (atrial fibrillation episode lasts for more than 7 days or requires medication or cardioversion to convert heart rhythm) for more than 3 years; b. Long-term persistent atrial fibrillation (Atrial fibrillation has been continued for more than 1 year when it is decided to take heart rhythm control measures); c. Paroxysmal atrial fibrillation with ECG recording; 4) Left ventricular end diastolic diameter (left ventricular long axis section) = 75mm; left atrial anteroposterior diameter (left ventricular long axis section) = 75mm; 5) EF value = 40%; 6) The clinical diagnosis can be as follows: d. Rheumatic mitral stenosis and regurgitation with or without tricuspid regurgitation; e. Rheumatic aortic stenosis and regurgitation, with or without tricuspid regurgitation; f. rheumatic mitral valve, aortic stenosis and regurgitation, with or without tricuspid regurgitation; g. Non-rheumatic mitral and/or aortic regurgitation with or without tricuspid regurgitation; 7) The patient signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients who require coronary artery bypass during the same period; 2) Emergency surgery patients; 3) A large number of thrombus in the left atrium; 4) Life expectancy = 3 years; 5) Cancer patients who have been diagnosed and treated; 6) Any factors that may be limited by the research team to limit intervention compliance; 7) The informed consent of the subject was not obtained; 8) Participating in other intervention studies; 9) Pregnant women or pregnancy plans during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour dynamic electrocardiogram;Chest X-ray;Echocardiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| INR;NTPro-BNP;Cardiac Function; | — |
Countries
China
Contacts
Public ContactLiu liming
The Second Xiangya Hospital of Central South University
Outcome results
None listed