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The high-risk gene interactions and the research of relationship in intestinal microbial flora on lifestyle intervention in overweight and obese patients.

The high-risk gene interactions and the research of relationship in intestinal microbial flora on lifestyle intervention in overweight and obese patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023767
Enrollment
Unknown
Registered
2019-06-11
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and obesity

Interventions

Control group:Conventional nursing

Sponsors

Shenzhen Nanshan Center for Disease Control and Prevention
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 50 years; 2. BMI:24-35 kg/m2; 3. Waist circumference:male>=90cm, female>=80cm; 4. No clear adverse previous medical history; 5. Participate in the research with clear purpose and high enthusiasm; 6. Permanent residence and have no plan to move to another place in the near future.

Exclusion criteria

Exclusion criteria: 1. Type 2 diabetes melitus,hypertension,renal insufficiency,gout,thyroid dysfunction,cerebrovascular disease,mental disease,acute infection,chronic wasting disease (TB infection, cancer, HIV). 2. Taking a drug that lowers blood lipid cholesterol,or have been used drug treatment of anti-obesity; had bariatric surgery;the weight change more than 5% before 3 months into the study. 3. With abuse of alcohol and drugs;change the smoking habits within 6 months or plan to quit smoking in the futrue 3 months. 4. Pregnancy in the past 6 months or breast feeding women,and consideration of pregnancy during the research stage. 5. Before the 3 months of screening,participation in another clinical trials.

Design outcomes

Primary

MeasureTime frame
Weight;BMI;Blood pressure;Obesity risk gene;Intestinal flora;

Secondary

MeasureTime frame
Waist size;Hipline size;Total cholesterol;Triglyceride;High density lipoprotein cholesterol;Low density lipoprotein cholesterol;Glycosylated hemoglobin;Glucose tolerance test;Blood uric acid;

Countries

China

Contacts

Public ContactLi Yong

Shenzhen Nanshan Center for Disease Control and Prevention

Liyong33668@sina.com+86 13688801846

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026