Benign and malignant diseases of pancreas
Conditions
Interventions
A:central pancreatectomy combined with end-to-end anastomosis reconstruction
B:traditional central pancreatectomy
Sponsors
Chinese People's Liberation Army (PLA) General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Obtain informed consent signed by the patient or his or her legal agent; 2. Compliance with the study plan and follow-up procedure; 3. Aged 18 to 70 years old male and female; 4. No surgical contraindications, able to tolerate radical surgery, ECOG behavioral status score 0-1, life expectancy = 12 weeks, ASA score = 2; 5. Diagnosed as benign or low-grade malignant lesions in the pancreatic neck and proximal body preoperatively according to clinical symptoms, imaging examination, tumor markers and other auxiliary examinations and postoperative pathology.
Exclusion criteria
Exclusion criteria: 1. Malignant tumors in other areas within the last 5 years; Patients with brain, lung, bone metastases or abdominal lymph node metastases; 2. patients with severe cardiopulmonary function, liver and renal function infection; 3. Infection of HCV, HIV, syphilis; 4. Women during pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pancreatic fistula(POPF) rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| operative time; postoperative morbidity rate;mortality rate;reoperation rate; | — |
Countries
China
Contacts
Public ContactLiu Rong
Chinese People's Liberation Army (PLA) General Hospital
Outcome results
None listed