Study for the correlation between the degree of cerebral edema and the content of tight junction proteins fragments in serum after craniocerebral surgery

Study for the correlation between Occludin level and peritumoral edema in patients with brain tumors during perioperative period

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023742

Enrollment

Unknown

Registered

2019-06-10

Start date

2019-06-10

Completion date

Unknown

Last updated

2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain tumor

Interventions

Occludin&#32

fragments

Gold Standard:The degree of brain edema was evaluated by CT/MRI as a reference standard.

Index test:serum&#32

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients with brain tumors who meet the criteria of surgery and perform surgical treatment; 2.Aged 18 to 80 years; 3. Obtain the informed consent of the patient or family member.

Exclusion criteria

Exclusion criteria: Serious liver and kidney dysfunction, diabetes, peripheral vascular embolism, autoimmune diseases, or serious digestive diseases.

Design outcomes

Primary

Measure	Time frame
Occludin;brain edema;SEN, SPE, ACC, AUC of ROC;	—

Countries

China

Contacts

Public ContactBaoguo wang

Sanbo Brain Hospital, Capital Medical University

wbgttyy@sina.com+86 13370185075

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026