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Study for the screening of TCM syndrome classification and molecular diagnostic markers in patients with cognitive impairment after strok

Study for the screening of TCM syndrome classification and molecular diagnostic markers in patients with cognitive impairment after strok

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023739
Enrollment
Unknown
Registered
2019-06-10
Start date
2019-06-09
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke cognitive impairment

Interventions

Sponsors

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients without cognitive impairment who met the diagnostic criteria and classification criteria of this study; Patients with mild and moderate PSCI after stroke were divided into phlegm-dampness syndrome group and non-phlegm-dampness syndrome group; 2. The history of stroke is confirmed by CT or MRI, and cognitive dysfunction must occur after cerebrovascular disease; 3. Life sign is stable, consciousness is sober; 4. Aged 35 to 70 years old; 5. Volunteer to participate in this research project.

Exclusion criteria

Exclusion criteria: 1. Complicated with severe primary diseases of the heart, liver, kidney and hematopoietic system; 2. Acute disturbance of consciousness; 3. Mild cognitive impairment was present before the stroke; 4. Other causes of dementia and brain dysfunction are mental and physical disorders; 5. With serious impairment of vision or hearing or speech interferes with rehabilitation; 6. In addition to cognitive impairment, there were no other focal signs and symptoms of cerebrovascular disease.

Design outcomes

Primary

MeasureTime frame
The differential proteins in plasma of each group were observed to search for key molecular markers;

Countries

China

Contacts

Public ContactBaoyun Qi

Dongzhimen Hospital attached to Beijing University of Chinese Medicine

qby0072009@sina.com+86 010-80816655/13810366232

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026