Coronary heart disease
Conditions
Interventions
Case series:Double guidewire balloon cutting+DCB
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. aged = 18 years, male and female; 2. Diagnosis of acute coronary syndrome (unstable angina or acute non-ST-segment elevation myocardial infarction); 3. Coronary angiography showed untreated primary coronary artery lesions (De Novo), lesion diameter stenosis >75%, reference diameter =2.5mm and =3.5mm, lesion length =10mm and =25mm; 4. Subjects volunteered to join the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnancy, or lactating women; 2. Acute ST-segment elevation myocardial infarction; 3. Cardiogenic shock, severe cardiac insufficiency or left ventricular dysfunction (left ventricular ejection fraction 221 µmol/L (2.5 mg/d1) or eGFR < 30 ml/min/1.73 m^2 (calculated according to the MDRD formula); 8. Severe liver damage (hild-Pugh grade C), biliary cirrhosis and cholestasis; AST, ALT greater than 3 times the upper limit of normal, or previous cirrhosis, portal hypertension, esophageal varices, etc.; 9. Life expectancy <12 months; 10. Unwilling or unable to provide informed consent; 11. The criteria for coronary angiography exclusion are as follows: (1) Chronic total occlusion disease; (2) left main lesion; (3) Moderate to severe tortuosity or severe calcification; (4) Severe coronary dissection (NHLBI type C-E) after expansion; (5) Coronary artery bypass graft lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Late lumen loss; | — |
Countries
China
Contacts
Public ContactBo Zhang
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed