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Endoscopic balloon dilatation combined with local betamethasone injection to prevent recurrence of anastomotic stenosis after ileocolic resection for Crohn's disease: a single-center prospective randomized controlled trial

Endoscopic balloon dilatation combined with local betamethasone injection to prevent recurrence of anastomotic stenosis after ileocolic resection for Crohn's disease: a single-center prospective randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023696
Enrollment
Unknown
Registered
2019-06-08
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chron's disease

Interventions

Group 1:EBD
Group 2:EBD combined with local injection of betamethasone

Sponsors

The Sixth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years old; 2. Confirmation of Crohn's disease; 3. After ileocolic resection, conventional endoscopy could not pass through the anastomotic stoma smoothly, and the Rutgeerts score of enteroscopy was less than i2; 4. There are clinical symptoms of proximal ileus after ileocolic resection; 5. Imaging findings showed that the proximal intestinal dilatation of the anastomotic stoma was more than 3 cm after ileocolic resection; 6. If there is intestinal fistula, the distance between the stricture and intestinal fistula is more than 5 cm.

Exclusion criteria

Exclusion criteria: 1. Severe coexistence diseases; 2. Malignant tumors; 3. Pregnancy or recent pregnancy intention; 4. Endoscopic contraindications; 5. contraindication of betamethasone injection.

Design outcomes

Primary

MeasureTime frame
Relapse rate;

Countries

China

Contacts

Public ContactChen Junrong

The Sixth Affiliated Hospital of Sun Yat-sen University

chenjunrong1985@126.com+86 15918779711

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026