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Construction of endometrial cancer drug screening system based on organoid model and clinical trial

Construction of endometrial cancer drug screening system based on organoid model and clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023682
Enrollment
Unknown
Registered
2019-06-07
Start date
2019-07-01
Completion date
Unknown
Last updated
2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

Case series:Specific sensitive drug therapy for patients with endometrial cancer based on in vitro cultured organs

Sponsors

Shanghai Tenth People's Hospital, Tongji University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) The patient is between 18-70 years old; (2) Endometrial diagnostic curettage pathology suggests endometrioid adenocarcinoma (including Bokman type I and II); (3) Signing informed consent and Ability to comply with follow-up actions.

Exclusion criteria

Exclusion criteria: (1) pregnant women; (2) those with other malignant tumors (such as cervical cancer, fallopian tube cancer, ovarian cancer, etc.); (3) those who have undergone other special types of treatment within the first half of the experiment: such as radiotherapy and chemotherapy, progesterone therapy, etc.; (4) Those who have combined with systemic immune diseases (such as rheumatic immune diseases, systemic lupus erythematosus, etc.).

Design outcomes

Primary

MeasureTime frame
progression free survival, PFS;Overall survival, OS;

Secondary

MeasureTime frame
imageological examination;Objective response rate, ORR;

Countries

China

Contacts

Public ContactZhongping Cheng

Shanghai Tenth People's Hospital, Tongji University

mdcheng18@263.net+86 13816686812

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026