The quality of postoperative recovery
Conditions
Interventions
Test group:After the fetus was delivered with a broken umbilical cord, intravenously infused with a loading dose of dexmedetomidine 0.5 µg/kg (diluted to 20 ml with saline) for 10 min, then changed to
Control group:The method was the same as the test group, and the same volume of physiological saline was infused.
Sponsors
Department of Anesthesiology, The Affliliated Hospital Of Xuzhou Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Full-term pregnancy ( =37 weeks); 2. Aged 20 to 40 years; 3. Height ranges from 150 to 170 cm; 4. Weight ranges from 50 to 90 kg; 5. American Society of Anesthesiologists (ASA) Grades: I to II; 6. Ability to understand and independently complete NRS and QoR-40 scores; 7. Ability to use PCA pump independently
Exclusion criteria
Exclusion criteria: 1. Pregnancy-induced hypertension syndrome; 2. HELLP syndrome; 3. Ischemic heart disease; 4. Liver and kidney dysfunction (serum creatinine > 2mg/dL glutamic-pyruvic transaminase or glutamic-oxaloacetic transaminase > 2 times normal value); 5. Long-term medication history (including NSAIDs opioid sedative-hypnotic psychotropic drugs); 6. History of alcohol abuse; 7. Heart rate below 50 beats per minute; 8. Drug allergy history of dexmedetomidine; 9. Taboos of combined spinal-epidural anesthesia; 10. Contraindication of combined spinal-epidural anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40; | — |
Secondary
| Measure | Time frame |
|---|---|
| EPDS;HADS;FS-14;NRS;NRS;The time when the parturient begins lactation; | — |
Countries
China
Contacts
Public ContactLiu Jindong
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed