Hypoparathyroidism
Conditions
Interventions
experimental group :using huaxi zhu's parathyroid gland typing
control group:using huaxi zhu's parathyroid gland typing
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. patients aged from 18 to 70 years who were diagnosed with PTC by preoperative fine needle cytology or histology examination; 2. indications for total thyroidectomy: the 2012 guidelines for diagnosis and treatment of thyroid nodule and differentiated thyroid cancer (Chinese version) shall govern: (1) Bilateral cancer lesions; (2) highly invasive subtypes, such as: high cell type of PTC, columnar cell type, diffuse sclerosis type, solid subtype; (3) local and distant metastasis has occurred, and 131I postoperative treatment is needed; (4) accompanied by extra-glandular invasion (such as subcutaneous adipose tissue, muscle, trachea, esophagus, carotid artery or mediastinal invasion, etc.); (5) the maximum diameter of the original oven is >1cm; 6 have thyroid cancer risk factors; PTC; Accompanied by contralateral thyroid nodules; 9 (9 BRAF) mutation positive patients; 3. indications for unilateral central region lymph node dissection: all PTC patients routinely underwent central region lymph node dissection on the affected side; 4. the indications for bilateral central lymph node dissection are in accordance with any of the following: (1) T3, T4 tumor; (2) cervical lymph node metastasis; (3) highly invasive subtypes; (4) anterior laryngeal and tracheal lymph node metastasis; 6 imaging or intraoperative findings of contralateral central lymph node enlargement; PTC; The maximum diameter of the tumor is >1cm. 9 (9 BRAF mutation positive patients; Patients have a strong desire to be more thorough; 5. before enrollment, the results of laboratory examination were in line with the operation conditions, and there were no contraindications; 6. volunteer to participate, sign informed consent, and be willing to follow up for a long time.
Exclusion criteria
Exclusion criteria: 1) preoperative fine needle puncture indicates non-ptc or suspicious PTC patients; 2) preoperative examination revealed abnormal PTH and serum calcium; 3) pregnant and lactating women (female patients were routinely excluded from urine pregnancy test); 4) previous allergy to research drugs; 5) unable to tolerate surgery for various reasons; 6) the researcher thinks that the group is not suitable for inclusion; 7) poor compliance of subjects, unwilling to participate; 8) With psychological, family, social or geographical constraints that may affect program compliance and follow-up time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PTH;blood calcium;blood magnesium;serum phosphate;blood vitamin D; | — |
Countries
China
Contacts
Public ContactSu Anping
Department of Thyroid Surgery, West China Hospital, Sichuan University
Outcome results
None listed