The fentanyl induced cough response during induction of general anesthesia
Conditions
Interventions
Group 1:After 3 min of pre-oxygenation, inject intravenously butorphanol 0.03 mg / kg
Group 2:After 3 min of pre-oxygenation, inject intravenously dizocine 0.1 mg / kg
Group 3:After 3 min of pre-oxygenation, inject intravenously Saline 5 ml
Sponsors
Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 99 patients underwent gynecologic surgery, aged 18-65 years, with ASA I~II, 18 kg/m2 <BMI <30 kg/m2.
Exclusion criteria
Exclusion criteria: Refusal to participate in this study,undergoing upper respiratory tract infection 2 weeks before surgery, glaucoma, aneurysm, asthma, history of chronic cough, history of smoking, chronic pain and long-term use of analgesics or sedatives, antidepressants, hypertension or long-term use of ace inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of the fentanyl induced cough response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative VAS analgesia score and Ramsay sedation score;Intraoperative hemodynamic parameters; | — |
Countries
China
Contacts
Public ContactHaifa Xia
Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed