polycystic ovary syndrome
Conditions
Interventions
1:Transvaginal ovarian drilling
2:small follicle drilling on the ovum pick-up
Sponsors
Reproductive Medical Center of Ruijin Hospital School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: We enrolled women who were diagnosed with PCOS based on the presence of all the Rotterdam criteria: 1. oligo- or amenorrhea (cycle>35 days); 2. bio-chemical/clinical hyperandrogenism (defined as a Ferriman-Gallwey score of =8, testosterone >2.5 nmol/l, and/or androstenedione >9.0 nmol/l); and 3. polycystic ovarian morphology (=12 follicles [2–9 mm] in at least 1 ovary). Patients with hyperinsulinemia were administered metformin for 2–3 months to decrease the insulin levels to normal levels. These patients were categorized into 3 groups: 1) poor responders (no or 15 dominant follicles developed within 2 weeks of stimulation, with the E2 level > 4200 pg/ml on the trigger day).
Exclusion criteria
Exclusion criteria: Previous ovarian surgery and co-existing endocrine diseases (diabetes mellitus, estrogen-dependent tumors, thyroid disease, Cushings syndrome, or congenital adrenal hyperplasia).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ovarian respone;Pregnancy outcome;hormone levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic clinical characteristics; | — |
Countries
China
Contacts
Public ContactBufang Xu
Reproductive Medical Center of Ruijin Hospital School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed