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The mechanism of cognitive impairment in chronic ischemic encephalopathy involved in brain default network and topological attribute changes

The mechanism of cognitive impairment in chronic ischemic encephalopathy involved in brain default network and topological attribute changes

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023610
Enrollment
Unknown
Registered
2019-06-04
Start date
2018-11-01
Completion date
Unknown
Last updated
2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moyamoya disease and carotid artery stenosis

Interventions

Moyamoya disease patient group:no
Carotid artery stenosis group:no
Moyamoya disease control group:no
Carotid artery stenosis control group:no

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with moyamoya disease DSA or MRI diagnosis of moyamoya disease standards, performance for unexplained unilateral or bilateral internal carotid artery end, brain artery and (or) before starting of middle cerebral artery stenosis or occlusion, accompanied by the bottom of the brain through the artery or brain surface capillaries expansion, namely the smoke, the formation of the veins; 2. Carotid ischemic cerebrovascular disease was diagnosed according to DSA and MR; 3. The signing of informed consent; 4. Aged 7 to 80 years old. The education level of the patient reached primary school and above.

Exclusion criteria

Exclusion criteria: 1. patients with vascular disease due to immune system disease; 2. patients who cannot receive revascularization surgery; 3. with other neuropsychiatric diseases that affect cognitive function (such as alzheimer's disease, Parkinson's disease, depression, anxiety, cerebral hemorrhage, hydrocephalus, craniocerebral trauma, etc.); 4. contraindications of magnetic resonance examination (with cardiac pacemaker, nerve stimulator, artificial metal heart valve and other metal foreign bodies, etc.).

Design outcomes

Primary

MeasureTime frame
Comprehensive cognitive scale;MRI image;

Countries

China

Contacts

Public ContactShihao He

Beijing Tiantan Hospital, Capital Medical University

dr.heshihao@qq.com+86 18610654120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026