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Observational study for early retinal neurovascular changes in diabetic patients

Observational study for early retinal neurovascular changes in diabetic patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023599
Enrollment
Unknown
Registered
2019-06-03
Start date
2019-06-10
Completion date
Unknown
Last updated
2019-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic retinopathy

Interventions

patients with type 1 diabetes mellitus + pantients wihtout fundus retinopathy:no intervention

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1) Definitive diagnosis of type 1 diabetes and age-matched non-diabetic controls; 2) Agree to participate in the study and sign an informed consent form;

Exclusion criteria

Exclusion criteria: 1. Other eye conditions affecting the macula and optic disc; 2. Refractive error > 3 diopter (D); 3. Eye trauma and history of surgery, strabismus or amblyopia; 4. Patients with diabetic retinopathy have been diagnosed by routine fundus examination; 5. Severe cataracts, vitreous opacity or other conditions that affect OCTA imaging (scan quality 21 mm Hg; 7. Combined with acute complications or infections of diabetes, complicated with allergic diseases; 8. Severe systemic diseases that may cause changes in retinal blood vessels; 9. There are any patients with uncontrolled clinical diseases (such as AIDS, active hepatitis, severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors).

Design outcomes

Secondary

MeasureTime frame
thickness of retinal nerve fiber layer;thickness of GC-IP complex;

Primary

MeasureTime frame
vessel density of retina;vessel density of radial radial peripapillary capillary;

Countries

China

Contacts

Public ContactSongtao Yuan

The First Affiliated Hospital of Nanjing Medical University

yuansongtao@vip.sina.com+86 15951088899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026