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The Study of Corneal Refractive Surgery Combined the Accelerated Collagen Cross-Linking in the high myopia and thin cornea myopic eyes

The Safety and Efficacy of Corneal Refractive Surgery Combined the Accelerated Collagen Cross-Linking in the high myopia and thin cornea myopic eyes

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023568
Enrollment
Unknown
Registered
2019-06-02
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

FS-LASIK ACXL:femtosecond laser assisted LASIK combined accelerated corneal collagen crosslinking
FS-LASIK: femtosecond laser assisted LASIK
LASEK ACXL:laser assisted subepithelial keratomileusis combined accelerated corneal collagen crosslinking
LASEK: laser assisted subepithelial keratomileusis

Sponsors

Shaanxi Institute of Ophthalmology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: High myopia eyes: myope diopter is less than -6.00D and astigmatism is less than 5.00D, or the minimum corneal thickness is in the range of 450 microns and 475 microns.The postoperatively corneal thinnest thickness should be no less than 400µm, and residual bed thickness should be no less than 280 microns. We follow the China corneal refractive surgery quality control consensus published in 2011.

Exclusion criteria

Exclusion criteria: The eyeball and/or circumocular inflammation; the abnormities of ocular appendages such as the eyelid defect, malformation, chronic dacryocystitis, etc; the keractoconus; severe dry eye; uncontrolled glaucoma; uncontrolled systematic diseases such as the desmosis, autoimmune diseases, diabetes, hypertention, etc.

Design outcomes

Primary

MeasureTime frame
postoperative refractive diopter;corneal refractive power;corneal fibrous morphology;

Secondary

MeasureTime frame
corneal epithelial thickness;uncorrected visual acuity;Dry eye questionnaire-5;

Countries

China

Contacts

Public ContactWei Wei

Shaanxi Institute of Ophthalmology, The First affiliated Hospital of Northwestern University

wills2015@foxmai.com+86 13772081522

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026