stroke
Conditions
Interventions
Low frequency rTMS group:1 Hz rTMS stimulation+rehabilitation therapy
High frequency rTMS group:10 Hz rTMS stimulation+rehabilitation therapy
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary signing of informed consent and willingness to participate in this study; 2. Aged 20 to 75 years, male or female; 3. According to the "Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke in China" (1995 edition), diagnosed as cerebral infarction; diagnosed as cerebral hemorrhage according to "Guidelines for the diagnosis and treatment of Chinese cerebral hemorrhage" (1995 edition); 3. Comply with the CRPS diagnostic criteria proposed by the IASP (Budapest standard); 4. Confirmed by CT or MRI; 5. MMSE Score meets the following criterria: 17 for those who never received education, 20 for those went to elementary school(less than 6 years), 20 for those who went to secondary school(more than 6 years); 6. Hand function impairment for paretic side, Brunnstrom level less than III, disease duration less than 12 months; 7.The vital signs are stable, without serious speech and cognitive impairments, which can be easily communicated and can be combined with rehabilitation therapy.
Exclusion criteria
Exclusion criteria: 1. Unable to complete motor imagery confirmed by motor and visual questionnaires; 2. Obvious cognition impairment; 3. Contraindications for MRI due to metal implants in body; 4. History of seizure; 5. Pregnant or feeding; 6. Severe cardiovascular, respiratory, liver and kidney diseases, unstable clinical symptoms; 7. Poor compliant and failed to complete the whole study; 8. Participating in other relevant clinical researchers at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| motor function; | — |
Secondary
| Measure | Time frame |
|---|---|
| ADL;MEP;Nerve conduction velocity; | — |
Countries
China
Contacts
Public ContactGao Tianhao
Huashan Hospital, Fudan University
Outcome results
None listed