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The role of TWEAK in vulgaris, pustular, and erythrodermic psoriasis

TWEAK is a critical cytokine linking vulgaris, pustular, and erythrodermic psoriasis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023554
Enrollment
Unknown
Registered
2019-06-02
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis

Interventions

Four groups:N/A

Sponsors

Second Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with vulgaris, pustular, and erythrodermic psoriasis who aged over 18 years old.

Exclusion criteria

Exclusion criteria: (1) have overlapping connective tissue disease, mixed connective tissue disease and undifferentiated connective tissue disease; (2) patients with immune skin diseases and cutaneous vasculitis, such as lupus erythematosus, allergic purpura, and white congestion; (3) have other inflammatory skin diseases, including eczema or atopic dermatitis; (4) other autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease (crohn's disease and ulcerative colitis); (5) patients with viral infectious skin diseases such as common warts; (6) in the period of severe and uncontrollable local or systemic acute and chronic infection; (7) history of hepatitis b or c;Or hiv-positive people; (8) patients with a history of benign or malignant tumor; (9) other situations in which the researcher considers it inappropriate to participate in the test; (10) received systemic treatments (e.g., systemic retinoids, cyclosporine, methotrexate or biological therapeutics) for psoriasis for at least three months.

Design outcomes

Primary

MeasureTime frame
TWEAK, IL-17, IL-22, IL-36?, IFN-?;

Countries

China

Contacts

Public ContactYumin Xia

Second Affiliated Hospital of Xi'an Jiaotong University

xiayumin1202@163.com+86 18209261277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026