Psoriasis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with vulgaris, pustular, and erythrodermic psoriasis who aged over 18 years old.
Exclusion criteria
Exclusion criteria: (1) have overlapping connective tissue disease, mixed connective tissue disease and undifferentiated connective tissue disease; (2) patients with immune skin diseases and cutaneous vasculitis, such as lupus erythematosus, allergic purpura, and white congestion; (3) have other inflammatory skin diseases, including eczema or atopic dermatitis; (4) other autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease (crohn's disease and ulcerative colitis); (5) patients with viral infectious skin diseases such as common warts; (6) in the period of severe and uncontrollable local or systemic acute and chronic infection; (7) history of hepatitis b or c;Or hiv-positive people; (8) patients with a history of benign or malignant tumor; (9) other situations in which the researcher considers it inappropriate to participate in the test; (10) received systemic treatments (e.g., systemic retinoids, cyclosporine, methotrexate or biological therapeutics) for psoriasis for at least three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TWEAK, IL-17, IL-22, IL-36?, IFN-?; | — |
Countries
China
Contacts
Second Affiliated Hospital of Xi'an Jiaotong University