Colorectal cancer
Conditions
Interventions
Gold Standard:1. physical examination - digital rectal examination
2. laboratory examination - blood routine, fecal occult blood test
3. imaging examination - X-ray angiography, ultrasound
4. endoscopy - rectal sigmoidoscopy
5. clinical outcomes
The gold standard is histopathology.
Index test:Disease 
or 
peripheral 
protein 
and 
Sponsors
Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Disease group inclusion criteria: 1. Aged greater than 18 years old, male or female; 2. Patients with colorectal cancer diagnosed by histopathological examination, or colorectal polyps, adenomas (high-grade intraepithelial neoplasia); 3. Acceptable root surgery; 4. A written informed consent form signed by the person or his legal representative; Healthy control group inclusion criteria: healthy people matched with the age of the disease group, no history of cancer, self-reported health.
Exclusion criteria
Exclusion criteria: 1. According to the patient's past history, suspected or indeed have a history of alcohol and drug abuse; 2. Intellectual or mental disorders, unable to cooperate with research; 3. Cannot cooperate or be lost to follow-up during follow-up; 4. Reluctant to undergo colonoscopy; 5. There are other serious diseases of the digestive tract, such as Crohn's disease, ulcerative colitis, etc.; 6. Serious heart, liver, lung, kidney, blood, endocrine system diseases; 7. pregnant women, lactating women or women of childbearing age who are ready to conceive; 8. The researcher believes that there is any situation that is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proteomics;SPF;Survival time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor metastasis site;Tumor pathological type; | — |
Countries
China
Contacts
Public ContactShu Zheng
Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed