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A research for MRGPRX2 mediates IgE-independent chronic urticaria

MRGPRX2 mediates a kind of chronic urticaria which is IgE-independent

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023532
Enrollment
Unknown
Registered
2019-06-01
Start date
2019-06-03
Completion date
Unknown
Last updated
2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic urticaria

Interventions

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Sponsors

Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 80 Years

Inclusion criteria

Inclusion criteria: Case group: 1. Age ranges from 6 to 80 years old; 2. Patients have no other disease in the near future; 3. Patients are diagnosed as chronic urticaria (The course of the disease is greater than or equal to 6 weeks); 4. Patients volunteere to participate in this project and be able to practitioners as required; 5. Patients have signed informed consent form, and be able to complete as required. Control group: 1. Healthy people. 2. No history of chronic urticaria; 3. There is no history of the family of chronic urticaria; 4. No disease in the near future.

Exclusion criteria

Exclusion criteria: 1. The patients of chronic urticaria have other disease; 2. Patients have indications of acute infection; 3. Patients have been diagnosed with physical urticaria (including artificial urticaria), cholinergic urticaria or urticaria vasculitis; 4. The patients are unable to cooperation or do not adhere to treatment or are judged poor adherence; 5. Pregnant women and nursing mothers; 6. Patients are joining in other clinical trials.

Design outcomes

Primary

MeasureTime frame
accuracy rate;Positive predictive value;Negative predictive value;

Countries

China

Contacts

Public ContactLangchong He

Xi'an Jiaotong University

helc@mail.xjtu.edu.cn+86 029 82655392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026