Clinical study for amniotic membrane transplantation in the treatment of diabetic keratopathy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023526

Enrollment

Unknown

Registered

2019-06-01

Start date

2019-06-15

Completion date

Unknown

Last updated

2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cornea

Interventions

Group 1:Amniotic membrane transplantation

Group 2:Wear Corneal contact lenses

Eligibility

Sex/Gender

All

Age

No minimum to 100 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis of diabetes mellitus; 2. Diabetic keratopathy with symptoms and/or signs, with corneal epithelial damage (using neurotrophic keratitis classification: grade 1: punctate keratopathy, rough corneal epithelium, abnormal tear film; grade 2: persistent corneal epithelial defect; grade 3: corneal ulcer, dissolution, perforation)

Exclusion criteria

Exclusion criteria: 1. Patients with active ocular infections; 2. patients with fundus diseases that need treatment; 3. patients with severe cardiovascular and cerebrovascular diseases; 4. patients with other acute diseases; 5. participants in other drug trials; 6. Researchers believe that there are other reasons not suitable for inclusion.

Design outcomes

Primary

Measure	Time frame
Time of corneal epithelial repair;Time of corneal epithelial healing;Time of complete healing of corneal epithelium;Healing rate of corneal epithelium during amniotic membrane removal;	—

Countries

China

Contacts

Public ContactJun Cheng

Shandong Eye Inistitute, Qingdao Eye Hospital

alice.567@163.com+86 18653280868

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026