Can 3% hypertonic saline reduce TBI child mortality and improve long-term neurological outcomes?

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023523

Enrollment

Unknown

Registered

2019-06-01

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic brain injury

Interventions

Two groups:3% saline versus mannitol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children under 16 years of age (excluding newborns), with craniocerebral injury within 24 hours of ICU, Glasgow coma score (GCS) 13 with mechanical ventilation patients

Exclusion criteria

Exclusion criteria: Patients with pre-existing neurological disease.

Design outcomes

Primary

Measure	Time frame
Glasgow coma scale;Injury severity score;Hypertonic drug use;Intracranial pressure (ICP) monitoring;	—

Countries

China

Contacts

Public ContactDang Hongxing

Children's Hospital of Chongqing Medical University

dhxdoc@163.com+86 13647683940

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026