To evaluate the feasibility and safety of endoscopic ultrasound-guided iodine-125 seed implantation in patients with unresectable esophageal caner and to explore the possibility of its replacing esophageal stenting.

Patients with unresectable esophageal cancer treated with endoscopic ultrasound-guided iodine-125 seed implantation

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023498

Enrollment

Unknown

Registered

2019-05-31

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal cancer

Interventions

esophageal cancer group:iodine 125 seed implantation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Esophageal squamous cell carcinoma or esophageal adenocarcinoma; 2.CT or endoscopic ultrasound guides that esophageal caner TNM staging is stage III or stage IV, and the lesion should be protruded; 3.No surgery or external radiotherapy indications, or patients refusing the therapy mentioned above; 4.There is a suitable puncture route; 5.Fitness score(Karnofsky score) =50; 6.Life expectancy is more than 3 months.

Exclusion criteria

Exclusion criteria: 1.Esophageal fistula; 2.Severe hemorrhagic tendency; 3.Unable to tolerate anesthesia or endoscopic ultrasound operation; 4.Unable to cooperate or quit midway; 5.Combined with other organs dysfunction.

Design outcomes

Primary

Measure	Time frame
dysphagia degree;quality of life;Changes of the primary tumor;	—

Countries

China

Contacts

Public ContactWen Li

Chinese PLA General Hospital

liwen2000@yahoo.com+86 13911589119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026