Patients undergoing elective cesarean section
Conditions
Interventions
Non-scarred uterus group:I.V. Oxytocin bolus or infusion(different dose)
Scarred uterus group:I.V. Oxytocin bolus or infusion(different dose)
Sponsors
Jiaxing Maternity and Child Health Care Hospital (Women and Children Affiliated Hospital, Jiaxing University)
Eligibility
Sex/Gender
Female
Age
19 Years to 45 Years
Inclusion criteria
Inclusion criteria: ASA I or II, aged 18 to 50 years, singleton pregnancies, scar uterus and the first time elective CD with a Pfannensteil incision. All enrolled patients received spinal anaesthesia and level of anesthesia is T4-T6.
Exclusion criteria
Exclusion criteria: Active labour, ruptured membranes, known drug allergy to oxytocin, significant obstetric disease (including pregnancy-induced hypertension or pre-eclampsia), known risk factors for postpartum haemorrhage (including abnormal placentation, giant gestation, uterine fibroids, history of postpartum haemorrhage or uterine atony), inherited or acquired coagulation disorder, and thrombocytopenia (platelet count ,100x10^9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxytocin dose;Estimate blood loss;Side effects;Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone; | — |
Countries
China
Contacts
Public ContactChangna Wei
Jiaxing Maternity and Child Health Care Hospital (Women and Children Affiliated Hospital, Jiaxing University)
Outcome results
None listed