Patients undergoing elective cesarean section
Conditions
Interventions
Youth scarred uterus group:I.V. oxytocin bolus or infusion (different dose)
Elderly scarred uterus group:I.V. oxytocin bolus or infusion (different dose)
Sponsors
Women and Children Affiliated Hospital, Jiaxing University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: ASA I or II, aged 18 to 50 years, singleton pregnancies, scarred uterus with a Pfannensteil incision. All enrolled patients received spinal anaesthesia and level of anesthesia is T4-T6.
Exclusion criteria
Exclusion criteria: Active labour, ruptured membranes, known drug allergy to oxytocin, significant obstetric disease (including pregnancy-induced hypertension or pre-eclampsia), known risk factors for postpartum haemorrhage (including abnormal placentation, giant gestation, uterine fibroids, history of postpartum haemorrhage or uterine atony), inherited or acquired coagulation disorder, and thrombocytopenia (platelet count,100x10^9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxytocin dose;Estimate blood loss;Uterine constraction score;Side effects;Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone; | — |
Countries
China
Contacts
Public ContactChangna Wei
Women and Children Affiliated Hospital, Jiaxing University
Outcome results
None listed