Type 2 Diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes; 2. The first time use Liraglutide; 3. 7% 10%.
Exclusion criteria
Exclusion criteria: 1. Impaired liver function, defined as plasma alanine transaminase(ALT) >2.5 times of upper normal limit; 2. Moderate and severe renal insufficiency defined as MDRD eGFR14 units for women or >21 units for men; 4. Any history of liver disease including metabolic or auto-immune liver diseases or viral hepatitis; 5. History or family history of medullary thyroid cancer(MTC), or multiple endocrine neoplasia type 2(MEN-2); 6. Congestive heart failure(NYHA III~IV); 7. Severe gastric-intestinal diseases; 8. Pregnancy or intention of becoming pregnant; 9. Known proliferative retinopathy or maculopathy requiring acute treatment as judged by the Investigator; Use of non-herbal Chinese medicine or other non-herbal local medicine with unknown/unspecified content. Herbal traditional Chinese medicine or other local herbal medicines may, at the Investigators discretion, be continued throughout the trial at an unchanged dose.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal fat quantification;renal blood flow;water diffusion; | — |
Secondary
| Measure | Time frame |
|---|---|
| weight;waist circumference;hip circumference;blood lipid;Body mass index;urine protein;HbA1c;Creatinine; | — |
Countries
China
Contacts
Tianjin Metabolic Diseases Hospital