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Clinical Study for Individualized Hormone Therapy in Patients with Peripheral Eosinophil-guided AECOPD: A Randomized Controlled Trial

Clinical Study for Individualized Hormone Therapy in Patients with Peripheral Eosinophil-guided AECOPD: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023427
Enrollment
Unknown
Registered
2019-05-27
Start date
2019-10-01
Completion date
Unknown
Last updated
2019-06-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

1:Guidance of glucocoticoids in patients with AECOPD by peripheal blood eosinophils
2:Traditional treatment

Sponsors

The Pepole‘s Hospital of Shapingba District
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Objectives 160 patients with AECOPD admitted to the Department of Respiratory Medicine of our hospital from October 1, 2019 to October 31, 2020 were selected. The clinical diagnosis conformed to the AECOPD diagnostic criteria established by the Global Initiative for Chronic Obstructive Pulmonary Disease in 2019. (1) Aged over 18 years; (2) Clear awareness, no language communication barriers, correct understanding of the content of communication, and fill in the informed consent. (3) Chronic obstructive pulmonary disease confirmed by pulmonary function test (FEV1/FVC < 0.70)

Exclusion criteria

Exclusion criteria: (1) Previous diagnosis of asthma or this diagnosis of asthma; (2) AECOPD patients with life-threatening acute respiratory failure (grade III) need invasive mechanical ventilation or intensive care unit; (3) Allergy to glucocorticoids; (4) Severe mental illness beyond the control of drugs (persons detained for the use of compulsory means in psychiatry); (5) Lactation and pregnancy; (6) Systemic fungal infection or tuberculosis infection.

Design outcomes

Primary

MeasureTime frame
Pulmonary function tests;Length of stay;

Countries

China

Contacts

Public ContactYuting Yin

The Pepole‘s Hospital of Shapingba District

769062037@qq.com+86 18696523911

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026