Lower rectal cancer
Conditions
Interventions
Group 1:Laparoscopic extralevator abdominoperineal resection (LELAPR)
Group 2:Laparoscopic abdominoperineal resection(LAPR)
Sponsors
Peking University Cancer Hospital & Institute
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Preoperative MRI and electron colonoscopy confirmed primary rectal cancer; 2.=5 cm from the anal verge to the lower margin of the tumor; 3.Inclusion age: 18-80 years old; 4.Inclusion time: September 2009 - December 2015.
Exclusion criteria
Exclusion criteria: 1.Combined with acute complications such as complete intestinal obstruction, major bleeding, and perforation; 2.Metasis existing; 3.Surgical contraindications existing; 4.Pregnancy,lactating femal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Circumferential resection margin rate;Intraoperative perforation rate;Local recurrence;Metastasis;Overall survival;Disease-free survival;Progression-free survival;Death; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time;Intraoperative blood loss;Hospitalization after surgery;Lymph nodes examined;Positive lymph nodes;Maximum tumor diameter;Postoperative hernia;Postoperative urinary retention;Postoperative intestinal obstruction;Postoperative perineal wound complications;pCR; | — |
Countries
China
Contacts
Public ContactMing Cui
Peking University Cancer Hospital & Institute
Outcome results
None listed