Therapeutic effect of three non-steroidal drugs on DDH in children and its effect on TNF-a and SP

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023415

Enrollment

Unknown

Registered

2019-05-26

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

developmental dysplasia of thehip,DDH

Interventions

Group A:Ketolactone tromethamine

Group B:Postoperative ibuprofen suspension

Group C:Post-operative administration of acetaminophen suppository

Eligibility

Sex/Gender

All

Age

1.5 Years to 3 Years

Inclusion criteria

Inclusion criteria: ? aged 1.5-3 years, weight 9.7-20Kg; ? X-ray showed complete dislocation of the hip joint, unilateral iliopsoas muscle adductor muscle release + Salter pelvic osteotomy + hip open reduction + tibia osteotomy + Femoral rotation osteotomy + hemifacial hernia external fixation. ? ASA (anaesthesia level) I-II level; ? did not receive analgesic pump treatment; ? no history of chronic pain opioids.

Exclusion criteria

Exclusion criteria: ? severe congenital heart disease untreated; ? known opioids and non-steroidal drugs allergic; ? neuropsychiatric dysfunction; ? sleep apnea syndrome; ? children with family communication dysfunction; ? children expression Children with severe abnormalities or who the doctor believes are not suitable for clinical studies.

Design outcomes

Primary

Measure	Time frame
Pain score;Sedation score;Inflammatory factor;Adverse reactions;cost analysis;	—

Countries

China

Contacts

Public ContactJinli Guo

The Second Hospital of Shanxi Medical University

gjlgbd@126.com+86 13546395590

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026