bronchial asthma and chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 75 years, male or female; 2) Comply with the GOLD guide or GINA guide; 3) Agree to enter the research project and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with acute respiratory diseases, atopy, other allergic diseases such as allergic rhinitis, allergic subjects, conjunctivitis and allergic dermatitis are excluded; 2) diagnosed lung cancer, bronchiectasis, diffuse lung disease (interstitial pneumonia, occupational lung disease, sarcoidosis, etc.), central airway stenosis; 3) Tuberculosis: active tuberculosis, old tuberculosis affects lung function (such as chronic fibrovascular tuberculosis, lung damage, tuberculous pleurisy caused by extensive pleural hypertrophy; 4) have undergone lobectomy and / or lung transplantation, pleural disease; 5) Known serious, uncontrollable diseases (including severe mental illness, mental retardation, neurological disease, malignancy, chronic liver disease, heart failure, autoimmune disease, chronic kidney disease) and/or possible Those who died during the March research cycle; 6) Very severe COPD patients with GOLD class IV; 7) Those who are participating in other clinical trials.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| ST2;IL-6R;IL-6mRNA;IL-33mRNA; | — |
Primary
| Measure | Time frame |
|---|---|
| IL-33;IL-6;fractional exhaled nitric oxide;Cell sorting count; | — |
Countries
China
Contacts
Shandong Provincial Hospital