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Therapeutic effect of three non-steroidal drugs on DDH in children and its effect on TNF-a and SP

Application and effect observation of different analgesia modes in postoperative developmental hip dislocation in children with integrated nursing mode

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023393
Enrollment
Unknown
Registered
2019-05-25
Start date
2016-09-10
Completion date
Unknown
Last updated
2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Developmental dysplasia of thehip

Interventions

Groups A:ketorolac tromethamine injection
Groups B:ibuprofen
Groups C:acetaminophen suppository

Sponsors

The Second Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. aged 1.5-3 years old, weight 9.7-20Kg; 2. X line showed complete dislocation of the hip joint, unilateral iliopsoas muscle adductor muscle release + Salter pelvic osteotomy + hip open reduction + tibia osteotomy + Femoral rotation osteotomy + hemifacial hernia external fixation; 3. ASA (anaesthesia level) I-II level.

Exclusion criteria

Exclusion criteria: 1. severe congenital heart disease untreated; 2. known opioids and non-steroidal drugs allergic; 3. neuropsychiatric dysfunction; 4. sleep apnea syndrome; 5. children with family communication dysfunction; 6. children expression Children with severe abnormalities or who the doctor believes are not suitable for clinical studies; 7. received analgesic pump treatment; 8. with history of chronic pain opioids.

Design outcomes

Primary

MeasureTime frame
serum tumor necrosis factor-a;substance P (SP);Pain score;Adverse reaction observation;—

Countries

China

Contacts

Public ContactJinli Guo

The Second Hospital of Shanxi Medical University

gjlgbd@126.com+86 13546395590

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026