Effect of blood flow shear force on endothelial glycocalyx during cardiopulmonary bypass

Correlation between wall shear stress and acute degradation of the endothelial glycocalyx during cardiopulmonary bypass

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900023389

Enrollment

Unknown

Registered

2019-05-25

Start date

2019-06-01

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiovascular disease

Interventions

Case series:no

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Cardiac function NYHA class II-III; echocardiography showed left ventricular ejection fraction (LVEF>35%); left ventricular end-diastolic diameter <80 mm; signed informed consent.

Exclusion criteria

Exclusion criteria: patients 70 years old; carotid stenosis >50% or plaques; secondary surgery and emergency surgery; cardiac function NYHA classification in VI-V; atrial fibrillation patients.

Design outcomes

Primary

Measure	Time frame
shear stress;Syndecan-1;Heparan sulfate;	—

Countries

China

Contacts

Public ContactWeijian Wang

The First Affiliated Hospital of Wenzhou Medical University

wangwj2002@hotmail.com+86 15168751789

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026