Acute necrotizing pancreatitis
Conditions
Interventions
A group:Low molecular weight heparin
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Aged = 18 and <85 years; 2) Meet AP diagnostic criteria; 3) Acute pancreatitis onset = 7 days; 4) CT diagnoses pancreatic necrosis and/or mixed necrosis.
Exclusion criteria
Exclusion criteria: 1) pregnant or lactating women; 2) any part of vascular thrombosis before enrollment; 3) severe active bleeding; 4) indications for emergency laparotomy: such as peritoneal organ perforation, abdominal cavity syndrome that is difficult to correct with conservative treatment; 5) those who are allergic to heparin; 6) refusing to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of portal vein thrombosis ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of pancreatic portal hypertension ;Incidence of abdominal bleeding;Incidence of organ failure;Mortality;Total hospital days;Hospital charge;Adverse event; | — |
Countries
China
Contacts
Public ContactNonghua Lv
The First Affiliated Hospital of Nanchang University
Outcome results
None listed