severe fever with thrombocytopenia syndrome
Conditions
Interventions
Sponsors
People's Liberation Army 154th Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: patients who have to meet all of following items: 1. Clinical diagnosis: diagnostic criteria in accordance with the Ministry of Health issued by the "fever with thrombocytopenia syndrome prevention and control guidelines" implementation. Mainly based on epidemiological history (epidemic season in the hills, forest, mountain and other places of work, life or travel history or 2 weeks before the onset of tick bites history), fever and other clinical manifestations and peripheral platelets or white blood cells decreased; 2. Pathogen diagnosis: SFTSV virus nucleic acid detection positive; 3. platelet count between 30-80*10^9/L; 4. Aged between 18-80 years old, male and female
Exclusion criteria
Exclusion criteria: patients who meet any one of the following criteria will be excluded: 1. Time between admission and the disease onset is more than 7 days; 2. With high chlorine acidosis, renal insufficiency and anuria and other contraindications; 3. Receiving antiviral drugs, immunomodulatory treatment within 6 months; 4. Combined with other pathogen infections, such as HIV, syphilis, Rickettsia, Lyme disease spiral or bar Biscuits and other pathogens that can cause similar symptoms; 5. Patients with chronic basic diseases such as cancer, tuberculosis, nephropathy; 6. Recent use of antiplatelet agents or antiallergic drugs; 7. Pregnant or lactating women; 8. No or unwilling signed informed consent; 9. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rate;Viral Load; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severe complication rate;days for platelet and white blood cells recovered to the normal level;Routine laboratory examination;Bleeding and vascular leakage symptoms;Immunological index; | — |
Countries
China
Contacts
Public ContactCui Ning
People's Liberation Army 154th Hospital
Outcome results
None listed