Functional Constipation
Conditions
Interventions
Sponsors
Beijing Puren Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: A total of fifty-six adults aged 18-80 years with functional constipation, who visited the hospital outpatient from November 1, 2015 to November 1, 2017, were enrolled in this study according to the diagnosis standards of the Rome III criterion. A two-week washout period was undertaken for patients receiving laxatives that might influence bowel habit.Fifty-two adults with a family history of gastrointestinal cancer that were scheduled for a colonoscopy examination at the same time were recruited for the CTT test and colonoscopy as the healthy control (HC) group. All subjects were receiving colonoscopies for routine screening purposes only, with no reported changes in bowel habits. We evaluated the symptoms of the control group based on the Wexner score.
Exclusion criteria
Exclusion criteria: Participants in FC group were excluded based on the following criteria: 1) A history of abdominal and pelvic surgery, 2) A history of gastrointestinal cancer, diabetes, Parkinsons disease, thyroid disease, or IBD, and 3) A history of pregnancy in one year before the test. Subjects in HC group were excluded if they had a significant current or previous medical history, were regularly taking medication (e.g., opioids, aluminized drugs, antidepressants, calcium antagonists) that may affect the GI or central nervous system, or had donated blood within the past six months, or Wexner score=2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Colon transit time;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactChunying Zhai
Beijing Puren Hospital
Outcome results
None listed