Association between driving pressure and postoperative pulmonary complications after lung cancer resection: a prospective randomized controlled study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023332

Enrollment

Unknown

Registered

2019-05-22

Start date

2019-05-31

Completion date

Unknown

Last updated

2021-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pulmonary complications after lung cancer resection

Interventions

Group D:Driving pressure guided one lung ventilation

Group P:PEEP 4 during one lung ventilation

Eligibility

Sex/Gender

All

Age

19 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status I ~ III; 2. Patients aged 19~75 years; 3. Patients undergoing lung cancer resection with single lung ventilation; 4. Patients with with cardiac function grade I ~ II assessed by electrocardiogram, echocardiography; 5. Food or semi-liquid intake is acceptable;

Exclusion criteria

Exclusion criteria: 1. Preoperative FEV1/FVC<50%; 2. Contraindication of PEEP: intracranial hypertension, bronchopleural fistula, hypoxic shock, right ventricular failure; 3. Involving drug allergy; 4. Patients with serious liver, kidney, hematopoietic system diseases; 5. Patients with serious complications such as pulmonary infection, atelectasis, emphysema, pulmonary heart disease and pleurisy; 6. Previous major chest surgery history or chemotherapy history.

Design outcomes

Primary

Measure	Time frame
postoperative pulmonary complications;	—

Countries

China

Contacts

Public ContactLonghui Cao

Sun Yat-sen University Cancer Center

caolh@sysucc.org.cn+86 13826092036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026