post-stroke cognitive disorder combined with insomnia
Conditions
Interventions
Experiment Group:Basic therapy + Cognitive rehabilitation training+ Modified Suanzaoren Decoction
Control group 1: Basic therapy + Cognitive rehabilitation training + Estazolam
Control group 2: Basic therapy + Cognitive rehabilitation training
Sponsors
Tongde Hospital of Zhejiang Province
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Cerebral hemorrhage cerebral infarction diagnosed by CT or MRI and the Live-Yin deficiency syndrome is diagnosed. 2. Mild cognitive disorder is diagnosed according to Expert consensus on management of poststroke cognitive impairment 2017and the insomnia is diagnosed according to Guidelines for the diagnosis and treatment of insomnia in Chinese adults. 3. Paticipants agree to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Stroke with disturbance of consciousness or disease that too serious to cooperate with the relevant examination 2. Serious mental disorder or have a history of mental illness. 3. Participants with severe aphasia, inability to write, sever cognitive decline that are hardly to cooperative. 4. Sever cardiopulmonary failure or other sever physical disease that cannot comply with treatment. 5.Insomnia or cognitive disorder (such as alzheimer's disease) before this onset of stroke. 6. Participants are taking drugs for the central nervous system, such as benzodiazepines, antidepressants and antipsychotics. 7. Participants are or had been in other clinical trials that may affect the outcome of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive evaluation;Sleep quality evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| activity of daily living (ADL);cerebral blood flow; | — |
Countries
China
Contacts
Public ContactZhu Mingjin
Tongde Hospital of Zhejing Province
Outcome results
None listed