Sequential therapy effects of HFNC on Patients with Thoracic Trauma combined with ARDS From Weaning: A prospective single-centered randomized controled study

Sequential therapy effects of HFNC on Patients with Thoracic Trauma combined with ARDS From Weaning: A prospective single-centered randomized control study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900023296

Enrollment

Unknown

Registered

2019-05-21

Start date

2019-05-21

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Trauma combined with ARDS

Interventions

1:HFNC

2: BIPAP

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Within 24 hours after routine tracheal intubation extraction, the patients met the following conditions: pulmonary contusion was significantly improved, no hemopneumothorax, pleural effusion was reduced, consciousness was clear, and spontaneous expectoration was possible; Temperature (< 38.0 ?); Tidal volume of spontaneous respiration (VT)3 ~ 5 ml/kg, frequency < 0 times/min, oxygen and index 300mmHg;Hemodynamics was stable (norepinephrine 0.05 g/kg.min, dopamine hydrochloride 5 g/kg.min). Hemoglobin 80g/L.

Exclusion criteria

Exclusion criteria: Younger than 15, older than 75; Patients with tracheotomy; Combined with craniocerebral trauma and disturbance of consciousness; Concomitant with other important organ injuries; Facial deformity.

Design outcomes

Primary

Measure	Time frame
survival rate and fatality rate;	—

Secondary

Measure	Time frame
PaO2/FiO2, PaCO2;reintubation rate;the length of hospital stay;	—

Countries

China

Contacts

Public ContactMa Li

Lanzhou University Second Hospital

mali1105@126.com+86 13893679654

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026