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Effect of berberine on blood glucose and lipid regulation in type 2 diabetes mellitus patients

Effect of berberine on blood glucose and lipid regulation in type 2 diabetes mellitus patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023238
Enrollment
Unknown
Registered
2019-05-18
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

single arm:On the basis of the original scheme combined with berberine, three times a day, each 0.3g, within 4 weeks

Sponsors

Healthcare Center for Shishan Street Community of Suzhou hign-tech zone
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed as type 2 diabetes mellitus, and no damage to target organs was found; 2. Age between 18 and 65 years(including 18 and 65 years old), male or female, no allergic history; 3. Taking alimentary control and exercise without treatment by any drug or with metformin only; 4. Blood glucose: fasting blood glucose among 6mmol/L and 11.1mmol/L, and/or postprandial blood glucose among 8mmol/L and 13.1mmol/L.

Exclusion criteria

Exclusion criteria: 1. Patients participating in other clinical trials; 2. Patients with reproductive needs or breastfeeding; 3. Patients with a history of abnormal thyroid function, hepatic and renal insufficiency or failure; 4. Anemia patients; 5. Patients with deficiency of glucose-6-phosphate dehydrogenase.

Design outcomes

Primary

MeasureTime frame
Fasting capillary blood glucose;Postprandial(2h) capillary blood glucose;Glycosylated hemoglobin;Fastinig serum insulin;Fasting serum peptide C;Blood lipid analysis;

Secondary

MeasureTime frame
Urine routine test;

Countries

China

Contacts

Public ContactDongping Cai

Healthcare Center for Shishan Street Community of Suzhou High-tech Zone

caidongping1985@163.com+86 13914019231

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026