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Research for the mechanism of nocturia in patients with obstructive sleep apnea

Research for the mechanism of nocturia in patients with obstructive sleep apnea

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900023229
Enrollment
Unknown
Registered
2019-05-17
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea

Interventions

OSA with nocturia group + non-nocturia group:no intervention

Sponsors

Nanfang Hospital, Southern Medical University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) patients with snoring, lethargy and other symptoms. (2) 18 to 65 years of age. (3) complete polysomnography and the data are valid. (4) full knowledge of the content of the study and signing of an informed consent form.

Exclusion criteria

Exclusion criteria: (1) other respiratory diseases with chronic bronchitis, COPD, asthma and other respiratory diseases that can cause chronic hypoxia. (2) cardiovascular diseases such as uncontrolled and diuretics affecting urination, coronary atherosclerotic heart disease, cardiac insufficiency, etc. (3) urinary system diseases such as persistent urinary incontinence, acute and chronic glomerulonephritis, pyelonephritis, nephrotic syndrome, prostate disease and so on. (4) patients with important physical disorders such as neuromuscular diseases, hematological diseases, autoimmune diseases, liver diseases, hyperthyroidism, hypothyroidism, malignant tumors and so on. (5) diagnosed and medicated treatment of diabetes and other diseases that may lead to increased nocturia. (6) acute coronary syndrome and/or cerebrovascular accident within three months. (7) those with congenital or mental illness, or those who are unable to cooperate with disturbance of consciousness. (8) pregnant and lactating women. (9) with a history of spinal trauma, spinal or pelvic surgery.

Design outcomes

Primary

MeasureTime frame
ANP;ß2-MG;

Secondary

MeasureTime frame
Number and volume of nocturia;Basic Nordic Sleep Questionnaire;I-PSS;OABSS;

Countries

China

Contacts

Public ContactAnyang Wei

Nanfang Hospital, Southern Medical University

profwei@126.com+86 13380092189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026