breast cancer
Conditions
Interventions
experimental group:heart health beverage
Sponsors
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Willingness to sign the written informed consent document. 2. Female patients aged between 18 and 70 years with left side of breast cancer, Karnofsky performance score =70 points; 3. Breast cancer who has indication to receive adjuvant radiotherapy (50Gy/25Fx); 4. Pathological confirm of invasive breast cancer with negative surgical margin; 5. Patients received Cardiotoxic drugs in adjuvant or neoadjuvant stage; 6. Cardiac function: all of the patients were required to have a left ventricular ejection fraction (LVEF) >50%; 7. Patients had a life expectancy of 12 months or more.
Exclusion criteria
Exclusion criteria: 1. Disatant metastasis; 2. Right side of breast cancer; 3. T1-2N0, received Mastectomy 4. History of cardiac disease; 5. Hepatic functionalanine aminotransferase (ALT) and aspartate aminotransferase(AST)>2×ULN; 6. Severe or uncontrolled infection; 7. Women who are pregnant, breastfeeding; 8. History of other malignant disease; 9. Drug allergy to study drug; 10. Enrolled in other clinical trials; 11. History of Thoracic Radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial enzymes;cardiac function; | — |
Secondary
| Measure | Time frame |
|---|---|
| QOL;OS; | — |
Countries
China
Contacts
Public ContactXu Cheng
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed