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Effect of different left lateral table tilt on neonatal acid–base status and maternal hemodynamics for elective cesarean delivery under spinal anesthesia

Effect of different left lateral table tilt on neonatal acid–base status and maternal hemodynamics for elective cesarean delivery under spinal anesthesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900023218
Enrollment
Unknown
Registered
2019-05-16
Start date
2019-06-01
Completion date
Unknown
Last updated
2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Supine hypotension syndrome

Interventions

Supine group:Supine cesarean section
15° tilt group :15 degrees left cesarean section
30° tilt group :30 degrees left cesarean section

Sponsors

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: singleton pregnancy at term via elective cesarean section; age from 18 to 40 years; height from 150 cm to 180 cm; American Society of Anesthesiologists (ASA) grade from I to II grade; and BMI less than 35 kg/m2.

Exclusion criteria

Exclusion criteria: Transverse lie, fetal macrosomia, uterine abnormalities (e.g., large fibroids, bicornuate uterus) and polyhydramnios, ruptured membranes, oligohydramnios, or intrauterine growth restriction; Women with gestational or nongestational hyptertension, diabetes, eclampsia, a hypertensive disorder or any condition associated with autonomic neuropathy (e.g., diabetes mellitus for more than 10 yr), with renal failure; Women have contraindications for spinal anesthesia; participants refused to sign informed consent.

Design outcomes

Primary

MeasureTime frame
Umbilical artery blood pH;

Secondary

MeasureTime frame
umbilical vein blood PH;umbilical artery blood partial pressure of oxygen;umbilical vein blood partial pressure of oxygen;umbilical artery blood BE;umbilical vein blood BE;umbilical artery blood HCO3-;umbilical vein blood HCO3-;fetal Apgar score (1 minute after birth) And 5 minutes);The incidence of nausea in pregnant women;The incidence of vomiting in pregnant women;The incidence of hypotension in pregnant women;The incidence of hypertension in pregnant women;The incidence of bradycardia in pregnant women;2 min (T1), 4 min (T2), 6 min (T3), 8 min (T4), 10 min (T5), 12 min (T6), 14 min (T7), 16 min (T8), 18 min (T9) , 20min (T10) blood pressure after subarachnoid injection;2 min (T1), 4 min (T2), 6 min (T3), 8 min (T4), 10 min (T5), 12 min (T6), 14 min (T7), 16 min (T8), 18 min (T9) , 20min (T10) heart rate after subarachnoid injection;Dosage and frequency of phenylephrine during surgery;Time interval from the completion of combined spinal and epidural anesthesia to the first use of phenylephrine;The time interval from the injection of the subarachnoid space to the delivery of the fetus;Skin incision to fetal delivery interval;Uterine incision to fetus delivery time interval;Dosage and frequency of epidural bupivacaine during surgery;Dosage and frequency of ephedrine during surgery;Dosage and frequency of atropine during surgery;

Countries

China

Contacts

Public ContactDunyi Qi

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University

qdy6808@163.com+86 15162159886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026